2nd Annual Musculoskeletal Research Symposium

April 19, 2019
8:00 AM - 5:00 PM

Miller-Ward
Alumni house

The second annual Musculoskeletal (MSK) Research Symposium will again represent a diverse and multidisplinary collaboration among the community of musculoskeletal researchers from universities across the southeast. We look forward to seeing you, and will post more details here as they become available.

Keynote Speaker: Regis O’Keefe, MD, PhD

Follow link to register: http://bit.ly/EmoryMSK 

Questions? Email Ali McClure (ali.rae.mcclure@emory.edu) or call 404-778-0861

2019 Schedule

7:00- 7:45 Registration & Continental Breakfast
7:45 - 8:00 Welcome & Introduction
Hicham Drissi PhD, Vice Chairman of Research, Professor, Department of Orthopaedics, Professor, Department of Cell Biology; Emory University School of Medicine

Session I: Bone Biology

Moderator: Neale Weitzmann, PhD, Associate Professor of Medicine, Department of Medicine; Emory University School of Medicine

8:00 - 8:15 Nutritional regulation of inflammation and bone quality:

George R. Beck Jr. PhD

Associate Professor of Medicine, Division of Endocrinology, Metabolism and Lipids, Emory University
8:15 - 8:20 Questions & Discussion
8:20 - 8:35 Disruptive Impact of Proteolytic Networks on Tissue Remodeling in Health, Disease, and Therapy

Manu Platt, PhD

Associate Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology;

Diversity Director, STC on Emergent Behaviors of Integrated Cellular Systems (EBICS)
8:35 - 8:40 Questions & Discussion
8:40 - 8:55 Genetics orofacial clefting: it’s all in the (phenotypic) details

Elizabeth Leslie, PhD

Assistant Professor, Department of Human Genetics, Emory University School of Medicine
8:55 - 9:00 Questions & Discussion
9:00 - 9:15 Building Cellular Diagnostic and Predictive Orthopedic Technologies 

Karen Burg, PhD

Professor, Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia
9:15 - 9:20 Questions & Discussion
Session II: 

Musculoskeletal Disease and Repair

Moderator: Ed Botchwey, PhD, Associate Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University

9:20 - 9:35 Clinical applications of Injectable MSC’s for Knee Osteoarthritis: Initiation of an Emory- led Multicenter, Randomized Clinical Trial Kenneth R. Mautner, MD
Associate Professor of Orthopaedics, Assistant Professor of Physical Medicine and Rehabilitation, Emory University School of Medicine; Director, Sports Medicine Physical Medicine & Rehabilitation Fellowship
9:35 - 9:40 Questions & Discussion
9:40 - 9:55 Development of Jagged1-based bone regenerative therapies to treat maxillary hypoplasia Steven Goudy, MD
Professor of Pediatric Otolaryngology, Emory University School of Medicine; Director, Division of Pediatric Otolaryngology, Children's Healthcare of Atlanta
9:55 - 10:00 Questions & Discussion
10:00 - 10:15 Osteocyte mechanosensation and bone adaptation to exercise

Meghan Lawrence, PhD

Associate Professor, Cellular Biology and Anatomy, Medical College of Georgia at Augusta University
10:15 - 10:20 Questions & Discussion
10:20 - 10:35 Role of SOXC-RELA molecular axis in synovial joint pathologies

Pallavi Bhattaram, PhD

Assistant Professor, Department of Orthopaedics and Cell Biology, Emory University School of Medicine
10:35 - 10:40 Questions & Discussion
10:40-10:55 Novel Small Molecule Inhibitors of Sclerostin with the Potential to Enhance Spinal Fusions

Steven Presciutti, MD

Assistant Professor of Orthopaedic Surgery; Chief of Spine Surgery, Atlanta VA Hospital
10:55-11:00 Questions & Discussion
11:00 - 11:10 Break
Session III:

Stem Cells and Tissue Regeneration

Moderator: Johnna Temenoff, PhD, Professor, Deputy Director, NSF Engineering Research Center on Cell Manufacturing Technologies, Co-Director, Regenerative Engineering and Medicine Center, Petit Institute for Bioengineering and Biosciences, Coulter Department of Biomedical Engineering; Georgia Institute of Technology and Emory University

11:10 - 11:25 Metabolomics in Stem Cell Therapy Manufacturing

Sakis Mantalaris, PhD

Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology
11:25 - 11:30 Questions & Discussion
11:30 - 11:45

Single cell RNA sequencing of the vertebral disc

Greg Gibson, PhD

Professor, School of Biological Sciences, Georgia Institute of Technology


11:45 - 11:50 Questions & Discussion
11:50 - 12:05 Engineering heterochronic parabiosis in 3D microphysiological system to study stem aging

Young Jang, PhD

Assistant Professor, School of Biological Sciences, Georgia Institute of Technology
12:05 - 12:10 Questions & Discussion
12:10 - 12:25 Therapeutic Cell Products: Achieving robust, reliable, and predictable production and results

Carolyn Yeago, PhD

Associate Director of Research at Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology
12:25 - 12:30 Questions & Discussion
12:30-1:30 Lunch and Poster Session

Keynote Presentation

Moderator: Hicham Drissi, PhD, Vice Chairman of Research, Professor, Department of Orthopaedics and Cell Biology; Emory University School of Medicine

1:30 - 2:20

Epigenetic regulation of chondrocytes in osteoarthritis Regis O’Keefe, MD, PhD Chairman, Department of Orthopaedic Surgery, Fred C. Reynolds Professor of Orthopaedic Surgery; Washington University

2:20 - 2:30

Questions & Discussions

Session IV: Junior Speakers

Moderator: Nick Willett, PhD, Assistant Professor of Orthopaedics; Emory University School of Medicine

2:35-2:45

Metabolomics-guided design of biomaterials for bone tissue engineering

Michail Klontzas, MD, PhD

Postdoctoral Fellow, The Wallace H. Coulter Department of Biomedical Engineering
Georgia Institute of Technology and Emory University

2:45-2:55

Hydrogel Surfaces Promote MSC Expansion and Proregenerative Priming for Rotator Cuff Muscle Healing

Molly Ogle, PhD

Postdoctoral Fellow, The Wallace H. Coulter Department of Biomedical Engineering
Georgia Institute of Technology and Emory University

2:55-3:05 Probiotic supplementation accelerates bone repair and prevents post-traumatic bone loss

Joseph Roberts

PhD Candidate, Laney Graduate School, Emory University

 
3:05-3:15 PGD: A new shape memory, bioresorbable elastomer for soft tissue repair

Harsha Ramaraju, PhD

Postdoctoral Fellow, The Wallace H. Coulter Department of Biomedical Engineering
Georgia Institute of Technology and Emory University
3:15-4:30  Closing Remarks & Social